We have designed an innovative program featuring major advances across the NR field. The program opens with a focus on women's health and hormone regulation. This will be followed by a session examining the role of NRs in tissue metabolic adaptations, highlighting NRs as molecular switches in metabolic regulation and disease with an emphasis on physiological balance. The third session will present recent advances in immunomodulation and inflammation, reflecting the expanding understanding of NRs in immune responses. As the conference progresses, it will address new insights into hormone-regulated networks and their impact on age-related diseases, including cancer and cardiometabolic diseases. The final day will explore emerging findings on orphan and adopted NRs in tissue-specific metabolic adaptations, followed by a session bridging fundamental science with novel therapeutic strategies. The conference will culminate in a forward-looking round table on the future directions of the field.

ORGANISERS:

Inés Pineda-Torra (CABIMER)

Mercedes Ricote (CNB-CSIC)

Chris Glass (UCSD)

Donald McDonnell (Duke University)

PROGRAM AT-A-GLANCE

Day 1 | 21 September 2026

From Signal to Action: The Molecular Dialogue in Women’s Hormone Regulation

Bright Sparks Session I (short talks)

Day 2 | 22 September 2026

Orchestrating Tissue-Specific Metabolic Adaptations

Molecular Switches, Major Impacts: Decoding Hormone Regulation in Immunomodulation

Bright Sparks Session II

Poster Session I & Network

Next-Gen Hormone Networks: Insights on Age-Related Diseases

Day 3 | 23 September 2026

Orphans & Adopted: The Not so New Kids on Block

Inflammation Reloaded: Nuclear Receptors at the Crossroads of Inflammation and Resolution

Bright Sparks Session III

Poster Session II and Networking Break

The Endocrine Revolution: Novel Therapeutic Approaches

Special Topic Roundtable:

The New Wave: Charting the Course for Future Nuclear Receptor Discovery.

**ENDOCRINE SOCIETY SCIENCE SUMMIT 2026**

https://www.endocrine.org/meetings-and-events/science-summits/science-summit-2026

REGISTRATION & ABSTRACT SUBMISSION: OPENS 15th JUNE 2026